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Poliomyelitisvirus (Typ 1) - Cytopathische Veränderungen in der Gewebekultur (HEp-2 und Affennierenepithel)

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Formal Metadata

Title Poliomyelitisvirus (Typ 1) - Cytopathische Veränderungen in der Gewebekultur (HEp-2 und Affennierenepithel)
Alternative Title Poliomyelitis Virus (Typ 1) - Cytopathological Changes in the Tissue Culture (HEp-2 and Monkey Kidney Epithelium)
Author Diefenthal, Wolfgang
Habermehl, Karl-Otto
License CC Attribution - NonCommercial - NoDerivatives 3.0 Germany:
You are free to use, copy, distribute and transmit the work or content in unchanged form for any legal and non-commercial purpose as long as the work is attributed to the author in the manner specified by the author or licensor.
DOI 10.3203/IWF/E-1142
IWF Signature E 1142
Publisher IWF (Göttingen)
Release Date 1967
Language Silent film
Producer IWF
Production Year 1966

Technical Metadata

IWF Technical Data Film, 16 mm, 122 m ; SW, 11 1/2 min

Content Metadata

Subject Area Medicine
Abstract Zytopathische Effekte menschlicher Epithelien und Affennierenepithel nach Poliomyelitisvirusinfektion. Es kommt zu Organellenverlagerung, Ausbildung eines hyaloplasmatischen Zellkernrandsaumes, Kernpyknose und Zytoplasmaverfall mit zytoplasmatischer Fadenausbildung. Stimulierung der Zellteilung infizierter Zellen.
The film shows the cytopathic changes of human epithelial cells and of epithelia of monkey kidneys in tissue culture after infection with poliomyelitis virus type 1. Under the influence of the infection certain cellular cytoplasm components are at first displaced into the region surrounding the cell nucleus, and a hyaloplasm is formed. Then pyknosis and dissociation of the cytoplasm occur with formation of a branched reticulum of fine cytoplasm filaments, which stick for some time to the bottom of the culture vessel. The stimulation of cell division observed in the cells infected with poliomyelitis virus is shown. After division the daughter cells show the cytopathic effect characteristic for this type of virus.
Keywords Gewebekultur / Pathologie
Poliomyelitis / Poliomyelitis-Virus
cytopathischer Effekt (CPE)
zytopathogene Effekte, virusale
Zelltod
Pyknose
cytopathic effect (CPE)
tissue culture / pathology
cytopathic effects, viral
cell death
poliomyelitis / poliomyelitis virus
pyknosis

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