Vesicular-Stomatitis-Virus (Stamm Indiana) - Cytopathische Veränderungen in der Gewebekultur (HEp-2)

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Title	Vesicular-Stomatitis-Virus (Stamm Indiana) - Cytopathische Veränderungen in der Gewebekultur (HEp-2)
Alternative Title	Vesicular-Stomatitis-Virus (Stamm Indiana) - Cytopathological Changes in the Tissue Culture (Mice Fibroblasts and HEp-2)
Author	Diefenthal, Wolfgang Habermehl, Karl-Otto
License	CC Attribution - NonCommercial - NoDerivatives 3.0 Germany: You are free to use, copy, distribute and transmit the work or content in unchanged form for any legal and non-commercial purpose as long as the work is attributed to the author in the manner specified by the author or licensor.
Identifiers	10.3203/IWF/E-1140 (DOI) 10.5240/0A6C-688A-B39A-8217-82D6-Z (EIDR)
IWF Signature	E 1140
Publisher	IWF (Göttingen)
Release Date	1967
Language	Silent film
Producer	IWF
Production Year	1966

IWF Technical Data

Film, 16 mm, 88 m ; SW, 8 min

Subject Area	Medicine
Abstract	Zytopathische Effekte des Virus auf menschliche epitheliale Zellen post infectionem. Im einzelnen wird auf die Zytoplasmaretraktion, auf die Kernpyknose, Pseudopodienentstehung und Zytolyse eingegangen. Trotz Infektion bleiben die Mitosen sichtbar. The film shows the cythopathic changes of human epithelial cells (HEp-2) in tissue culture after infection with vesicular stomatitis virus. The virus infection initially causes retraction of the cytoplasm and minor pyknosis of the nucleus. Later on blister movements are seen, and extended filamentous protrusions of the cell membrane develop. These connect the remnants of the cell, which is shrinking increasingly, with the bottom of the culture vessel.
Keywords	Viruskrankheiten / Physiopathologie cytopathischer Effekt (CPE) zytopathogene Effekte, virusale Vesicular-Stromatits-Virus Blisterbewegung cytopathic effect (CPE) blister movement vesicular stomatitis virus virus diseases / physiopathology cythopathic effects, viral Encyclopaedia Cinematographica