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Proteus - L-Phase durch Penicillineinwirkung

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Formal Metadata

Title Proteus - L-Phase durch Penicillineinwirkung
Alternative Title Proteus - L-Phase as a Result of the Effect of Penicillin
Author Poetschke, Gerd
License No Open Access License:
German copyright law applies. This film may be used for your own use but it may not be distributed via the internet or passed on to external parties.
DOI 10.3203/IWF/E-273
IWF Signature E 273
Publisher IWF (Göttingen)
Release Date 1960
Language Silent film
Producer IWF
Production Year 1959

Technical Metadata

IWF Technical Data Film, 16 mm, 90 m ; SW, 8 1/2 min

Content Metadata

Subject Area Medicine
Abstract Veränderungen von Proteus unter hohen Penicillindosen zu Sphäroplasten, die später über amöboide Gebilde zu sogenannten L-Kolonien heranwachsen.
With Proteus the action of higher concentrations of penicillin leads to the formation of the so-called L-phase. First small round structures emerge from the bacterial rods, rapidly enlarging to spheroplasts. These grow into "amoeboid" structures in which vacuoles develop. The spheroplasts multiply and in some places grow deeply into the culture medium where they form the so-called L-colonies. When the penicillin action is suspended there is a gradual regression of the described events and gradually rod-like structures develop again which divide transversely. A stable L-phase may also develop where this regression can no longer occur. Its multiplication is demonstrated. The results of quantitative evaluation are described in detail in the accompanying text.
Keywords Bakterien
Arzneimitteleffekte / Bakterien
pharmacodynamics / bacteria

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