I will describe work in progress, parts of which are joint with Marcelo Alves. Let L be a knot or link in the 3-sphere. I will explain how one can count minimal surfaces in hyperbolic 4-space which have ideal boundary equal to L, and in this way obtain a knot invariant. In other words the number of minimal surfaces doesn’t depend on the isotopy class of the link. These counts of minimal surfaces can be organised into a two-variable polynomial which is perhaps a known polynomial invariant of the link, such as HOMFLYPT. “Counting minimal surfaces” needs to be interpreted carefully here, similar to how Gromov-Witten invariants “count” J-holomorphic curves. Indeed I will explain how this “minimal surface polynomial" can be seen as a Gromov-Witten invariant for the twistor space of hyperbolic 4-space. This leads naturally to a new class of infinite-volume 6-dimensional symplectic manifolds with well behaved counts of J-holomorphic curves. This gives more potential knot invariants, for knots in 3-manifolds other than the 3-sphere. It also enables the counting of minimal surfaces in more general Riemannian 4-manifolds, besides hyperbolic space.