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Ascorbic Acid and Cancer

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Ascorbic Acid and Cancer
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340
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Eight years after he had received a Nobel Prize in Chemistry for his fundamental contributions to stereochemistry, Sir Derek Barton attended the Lindau Nobel Laureate Meetings for the first time. He obviously liked their atmosphere and subsequently returned four times. It’s well worth listening to his talk. It offers a good deal of British pragmatism and humor, combined with the clear and confident sobriety of a scientist, which he also employs to explain why he had chosen a rather nonchemical topic. “This talk was inspired by a letter that I received some years ago from a number of American sociologists who wanted me to write an article how terrible the world was and how we were suffering from the most dreadful crises that mankind had ever suffered from (…) As far as I am concerned, the world is in a better shape than it’s been ever before and I am optimistic about its future and therefore I was pleased to write an article and I was somewhat surprised that this article was never published."Compared to the two World Wars and the big economic depression he had survived, Barton continues, most of the current crises did not appear dramatic to him. He distinguishes three classes of crises: Imaginary, artificial and real crises and then looks at “some of the crises the world press tells us we are suffering from” in terms of these categories. Presently, pollution for example, compared to “the thick, yellow London fog” of former times, appeared to be an imaginary crisis. The energy crisis is an artificial one for Barton, provoked by OPEC’s international monopoly. He is confident that science will find ways to overcome imminent energy shortages. In this context, he criticizes the “almost hysterical reaction in Germany to the proposal of building nuclear power stations”. All other crises he analyzes - global food supply, overpopulation and economic recession – Barton judges for various reasons as still being artificial – except for one: the danger of a nuclear war. While nobody knew exactly how many nuclear devices existed in the world, everybody knew that “it’s quite enough to kill off the population of the world several times.” On a statistical basis, Barton says, there had been at least one or two major wars every century: “Have we the right to believe that suddenly history of mankind is going to change?” Even if the balance of terror prevented the super powers to attack each other, “nuclear weapon technology is going to spread around the world (…) So we are going to come some time to a situation where a country in a last defense will use nuclear weapons or when some mad dictator will get hold of them and will use them in his madness.”Nevertheless, Sir Derek is “modestly optimistic because for the first time in human history we have seen a group of countries come together and give up some of their sacred national sovereignty”. Although it is, as he mentions, not customary in the UK to say something nice about the “Common Market”, he praises the predecessor of the European Union, as if anticipating the Nobel Peace Prize of 2012. Nations ought to have morality. They should learn “to work together in the same way as individuals work together to make up a family group”. If they succeed in doing so, “we may have a chance to evolve”. Joachim Pietzsch
Pauling, LinusChemistryNobeliumChemical bondChemical structureMultiprotein complexPharmaceutical drugTheoretische ChemieNutrientCancerLactitolMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondMultiprotein complexChemical structureDeathList of causes of death by rateAgeingRiver mouthMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondChemical structureMultiprotein complexBarton, DerekCancerHyaluronsäureGolgi apparatusRadioactive decayChemotherapyMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondMultiprotein complexChemical structureBarton, DerekCancerSurvival skillsLactitolMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondChemical structureMultiprotein complexCancerReaction mechanismMetastasisWine tasting descriptorsBottling lineCell (biology)Controller (control theory)Meeting/Interview
Pauling, LinusChemistryNobeliumChemical bondMultiprotein complexChemical structureBarton, DerekWine tasting descriptorsController (control theory)Reaction mechanismCancerCell (biology)EnzymeHope, ArkansasHyaluronsäureTumorMeeting/Interview
ChemistryPauling, LinusNobeliumChemical bondChemical structureMultiprotein complexBarton, DerekPhysiologyBase (chemistry)InhibitorTumorAbbruchreaktionController (control theory)MixtureCancerMeeting/Interview
ChemistryPauling, LinusNobeliumChemical bondChemical structureMultiprotein complexBarton, DerekAbbruchreaktionCancerOctane ratingISO-Komplex-HeilweiseRiver sourceOrganische ChemieMeeting/Interview
ChemistryPauling, LinusNobeliumChemical bondChemical structureMultiprotein complexBarton, DerekAscorbic acidConnective tissueCancerAcidScarBiosynthesisAageFaserverbundwerkstoffCollisionPolymerGlykolsäureMeeting/Interview
NobeliumChemistryPauling, LinusChemical bondMultiprotein complexChemical structureBarton, DerekConcretionHyaluronsäureShear strengthAscorbic acidCancerController (control theory)ToxinMeeting/Interview
ChemistryPauling, LinusNobeliumChemical bondMultiprotein complexChemical structureBarton, DerekScarAngiotensin-converting enzymeInhibitorAscorbic acidSodiumWine tasting descriptorsMeeting/Interview
NobeliumChemistryPauling, LinusChemical bondMultiprotein complexChemical structureBarton, DerekAscorbic acidReaction mechanismWine tasting descriptorsNutrientCancerRedoxCarbon (fiber)GasMeeting/Interview
Pauling, LinusChemistryNobeliumChemical bondMultiprotein complexChemical structureBarton, DerekImmunologyCancerCell (biology)GesundheitsstörungMoleculeChromosomenaberrationHemoglobinSickleMeeting/Interview
ChemistryNobeliumPauling, LinusChemical bondMultiprotein complexChemical structureBarton, DerekHemoglobinChromosomenaberrationGesundheitsstörungCancerMeeting/Interview
ChemistryPauling, LinusNobeliumChemical bondMultiprotein complexChemical structureBarton, DerekCancerElectronic cigarettePeriodateNicotinamideVitaminNiacinArzneimitteldosisExplosionMeeting/Interview
NobeliumPauling, LinusChemistryChemical bondMultiprotein complexChemical structureBarton, DerekNiacinFoodNutrientFaserplatteAscorbic acidBlind experimentArzneimitteldosisScarAcidAzo couplingMeeting/Interview
ChemistryNobeliumPauling, LinusChemical bondMultiprotein complexChemical structureBarton, DerekAzo couplingAscorbic acidController (control theory)AgricultureGesundheitsstörungConcentrateMeeting/Interview
NobeliumChemistryPauling, LinusChemical bondMultiprotein complexChemical structureGesundheitsstörungVitaminNutrientChemical compoundWursthülleAscorbic acidBattery (electricity)WaterfallConnective tissueLeakOrganische ChemieCollagenJoint (geology)Blood vesselDeathMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondMultiprotein complexChemical structureBarton, DerekCollagenAscorbic acidVitaminFunctional groupAreaLactitolMeeting/Interview
ChemistryPauling, LinusNobeliumChemical bondChemical structureMultiprotein complexBarton, DerekVitamin B1Chemical plantAzo couplingGrowth mediumVitaminFoodAageAtomMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondMultiprotein complexChemical structureBarton, DerekChemical plantFoodVitamin B1Ascorbic acidFunctional groupBase (chemistry)GeneCarbon dioxideScarWine tasting descriptorsAcidEnzymeMaterials scienceBody weightSetzen <Verfahrenstechnik>Meeting/Interview
Pauling, LinusNobeliumChemistryChemical bondMultiprotein complexChemical structureBarton, DerekEnzymeThiazoleSetzen <Verfahrenstechnik>PyrimidineSense DistrictVitaminNiacinVitamin B1PyridoxinePH indicatorChemical plantCrack cocaineCarbon dioxideMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondChemical structureMultiprotein complexBarton, DerekAscorbic acidSpeciesReaction mechanismChemical plantClayFoodCelluloseCollagenMeeting/Interview
NobeliumChemistryPauling, LinusChemical bondMultiprotein complexChemical structureBarton, DerekCarbon dioxideMoleculeProcess (computing)Man pagePrecursor (chemistry)Common landAscorbic acidCollagenChemical plantFoodBody weightAcidMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondMultiprotein complexChemical structureBarton, DerekEnzymeFoodAscorbic acidScarSetzen <Verfahrenstechnik>Meeting/Interview
ChemistryNobeliumPauling, LinusChemical bondChemical structureMultiprotein complexBarton, DerekBody weightGasAscorbic acidGrowth mediumFoodElephantiasisMeeting/Interview
NobeliumPauling, LinusChemistryChemical bondChemical structureMultiprotein complexBarton, DerekBody weightCancerMeeting/Interview
ChemistryNobeliumPauling, LinusChemical bondMultiprotein complexChemical structureBarton, DerekHematiteGemstoneMedicalizationTube (container)ScarWine tasting descriptorsAssetAscorbic acidMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondMultiprotein complexChemical structureBarton, DerekAscorbic acidAzo couplingGeneBerylliumTube (container)ElektronentransferAssetFoodMeeting/Interview
ChemistryPauling, LinusNobeliumChemical bondMultiprotein complexChemical structureBarton, DerekKatalaseChromosomeFoodGesundheitsstörungTube (container)Powdered milkNutrientFaserplatteBerylliumRiver mouthMeeting/Interview
NobeliumChemistryPauling, LinusChemical bondMultiprotein complexChemical structureBarton, DerekFeed (film)WursthülleDiet foodMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondChemical structureMultiprotein complexBarton, DerekAscorbic acidScarBody weightController (control theory)CancerReaction mechanismErdrutschMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondChemical structureMultiprotein complexBarton, DerekVitalismAscorbic acidFunctional groupScarVitaminNutrientRing strainWursthülleChain (unit)Meeting/Interview
NobeliumChemistryPauling, LinusChemical bondMultiprotein complexChemical structureBarton, DerekRing strainFunctional groupWursthülleErdrutschHomöostaseEnzymeCofactor (biochemistry)AgricultureMeeting/Interview
ChemistryPauling, LinusNobeliumChemical bondChemical structureMultiprotein complexBarton, DerekCofactor (biochemistry)EnzymeGeneAusgangsgesteinCombine harvesterConcentrateGenetic disorderCoalActive siteChromosomenaberrationMeeting/Interview
NobeliumPauling, LinusChemistryChemical bondChemical structureMultiprotein complexBarton, DerekUreaAcidGesundheitsstörungEnzymeCombine harvesterChromosomenaberrationCofactor (biochemistry)AreaVitaminVitamin B12Meeting/Interview
Pauling, LinusChemistryNobeliumChemical bondMultiprotein complexChemical structureBarton, DerekGesundheitsstörungVitaminErdrutschGrowth mediumCofactor (biochemistry)Ascorbic acidBody weightExplosionMeeting/Interview
ChemistryNobeliumPauling, LinusChemical bondMultiprotein complexChemical structureBarton, DerekAscorbic acidHandelsdüngerBody weightScarAcidErdrutschFumigationPig ironMeeting/Interview
ChemistryPauling, LinusNobeliumChemical bondChemical structureMultiprotein complexBiosynthesisWine tasting descriptorsCollagenAscorbic acidLysineHydroxylResidue (chemistry)Chemical reactionScarAcidProlineMoleculeInitiation (chemistry)MedicalizationGesundheitsstörungWoundArzneimitteldosisColumbia RecordsMeeting/Interview
ChemistryPauling, LinusNobeliumChemical bondMultiprotein complexChemical structureBarton, DerekErdrutschArzneimitteldosisSodiumConcentrateAscorbic acidScarGesundheitsstörungController (control theory)CancerExplosionAreaMeeting/Interview
Pauling, LinusChemistryNobeliumChemical bondMultiprotein complexChemical structureBarton, DerekAscorbic acidErdrutschCancerAssetMeeting/Interview
NobeliumPauling, LinusChemistryChemical bondChemical structureMultiprotein complexBarton, DerekSalt (chemistry)FireCarbon dioxideKohlenhydratchemieAcidSerum (blood)Klinisches ExperimentAscorbic acidOctane ratingSystemic therapyMeeting/Interview
Pauling, LinusChemistryNobeliumChemical bondChemical structureMultiprotein complexBarton, DerekCycloheptatrienAscorbic acidGesundheitsstörungErdrutschCarbon (fiber)KorkenTable wineAntibacterialCell (biology)PhagocyteSeparation processWhite blood cellReaction mechanismConcentrateScarFibrocyteMeeting/Interview
ChemistryPauling, LinusNobeliumChemical bondChemical structureMultiprotein complexBarton, DerekCell (biology)Sea levelBlock (periodic table)Rock (geology)Activity (UML)White blood cellProcess (computing)CancerActive siteMeeting/Interview
NobeliumChemistryPauling, LinusChemical bondMultiprotein complexChemical structureSalt (chemistry)Amino acidExplosionComposite materialBiomolecular structureProteinTrace elementMeeting/Interview
NobeliumPauling, LinusChemistryChemical bondChemical structureMultiprotein complexBarton, DerekPig ironEsteraseAscorbic acidErdrutschOctane ratingLymphocyteVolumetric flow rateCancerMeeting/Interview
ChemistryNobeliumPauling, LinusChemical bondChemical structureMultiprotein complexBarton, DerekStimulantOctane ratingCancerAntigenLymphocyteActive siteBiogenesisMeeting/Interview
NobeliumChemistryPauling, LinusChemical bondChemical structureMultiprotein complexBarton, DerekDiet foodSozialepidemiologieAscorbic acidCancerSeparation processErdrutschBET theorySunscreenWine tasting descriptorsMeeting/Interview
NobeliumPauling, LinusChemistryChemical bondChemical structureMultiprotein complexBarton, DerekErdrutschMortality rateGolgi apparatusCigaretteSmoking (cooking)Human subject researchScarWine tasting descriptorsAssetISO-Komplex-HeilweiseSunscreenAscorbic acidMeeting/Interview
NobeliumChemistryPauling, LinusChemical bondChemical structureMultiprotein complexBarton, DerekMortality rateCancerGesundheitsstörungAgeingMeeting/Interview
Pauling, LinusChemistryNobeliumChemical bondChemical structureMultiprotein complexBarton, DerekAscorbic acidNutrientAcidPeriodateWursthülleController (control theory)Drop (liquid)ErdrutschMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondMultiprotein complexChemical structureBarton, DerekErdrutschCancerWursthülleExplosionAbbruchreaktionActive siteAscorbic acidMedical historyOctane ratingMeeting/Interview
ChemistryNobeliumPauling, LinusChemical bondMultiprotein complexChemical structureBarton, DerekMortality rateOctane ratingCell growthController (control theory)Recreational drug useWursthülleAscorbic acidPainAppetiteMeeting/Interview
NobeliumChemistryPauling, LinusChemical bondMultiprotein complexChemical structureBarton, DerekCell (biology)GesundheitsstörungSedimentationSerum (blood)Red blood cellOctane ratingRapidCancerScarMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondMultiprotein complexChemical structureBarton, DerekFoodScurvyVitaminGesundheitsstörungBerylliumRecreational drug useAzo couplingCancerAusgangsgesteinMeeting/Interview
NobeliumPauling, LinusChemistryChemical bondChemical structureMultiprotein complexBarton, DerekFireAageErdrutschCancerAbbruchreaktionAscorbic acidMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondChemical structureMultiprotein complexBarton, DerekController (control theory)Ascorbic acidChemotherapyCancerMatchRecreational drug useToxicityActive siteSurvival skillsSeparation processMeeting/Interview
NobeliumChemistryPauling, LinusChemical bondMultiprotein complexChemical structureBarton, DerekController (control theory)Survival skillsCancerGesundheitsstörungForkhead-GenLeavening agentMeeting/Interview
ChemistryNobeliumPauling, LinusChemical bondChemical structureMultiprotein complexGesundheitsstörungWursthülleCancerSolutionChemotherapyAscorbic acidActive siteRecreational drug useToxicityCarbon (fiber)GasAlopeciaScarScurvyMeeting/Interview
Pauling, LinusChemistryNobeliumChemical bondMultiprotein complexChemical structureBarton, DerekChemotherapyScurvyWursthülleAlopeciaToxicityActive siteWine tasting descriptorsRecreational drug useRiver sourceReaction mechanismSystemic therapyAction potentialMeeting/Interview
NobeliumPauling, LinusChemistryChemical bondChemical structureMultiprotein complexBarton, DerekCancerChemotherapyScurvyLife expectancyAscorbic acidMeeting/Interview
NobeliumChemistryPauling, LinusChemical bondChemical structureMultiprotein complexAscorbic acidCarbon (fiber)CancerChemistGasScurvyWursthülleFoodMeeting/Interview
ChemistryPauling, LinusNobeliumChemical bondMultiprotein complexChemical structureBarton, DerekCancerAscorbic acidMeeting/Interview
Pauling, LinusNobeliumChemistryChemical bondChemical structureMultiprotein complexMeeting/Interview
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