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Expanding the toolbox of cytochrome P450s through enzyme engineering

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Logo of Beilstein-Institut zur Förderung der Chemischen WissenschaftenBeilstein-Institut zur Förderung der Chemischen Wissenschaften
 Turner, Nicholas O’Reilly, Elaine Kelly, Paul Eichler, Anja

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Expanding the toolbox of cytochrome P450s through enzyme engineering
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163
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CC Attribution - NoDerivatives 4.0 International:
You are free to use, copy, distribute and transmit the work or content in unchanged form for any legal purpose as long as the work is attributed to the author in the manner specified by the author or licensor.
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Release Date2013
LanguageEnglish

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Abstract
This video highlights the importance of cytochrome P450s in academia and industry and explains how our research group broadens the substrate range of these biocatalysts through enzyme engineering. We showcase a typical high-throughput assay and describe our procedure for carrying out whole-cell biotransformations.
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