Much of the fundamental research in computer science has been driven by the needs of those attempting to utilize computing for various applications, such as health. Shwetak Patel will describe a collection of his research projects and those from the research community in global health that is now having an influence on how to approach the current global COVID Pandemic. These projects follow the theme of finding unique signals and biomarkers in order to enable access and scale by leveraging existing hardware and data. His remarks will underscore the potential advances in health and clinical science through the convergence of sensing, machine learning, public policy, ethics, and human-computer interaction.