UCI Chem 51C Organic Chemistry (Spring 2012) Lec 03. Organic Chemistry -- Reactions of Organometallic Reagents -- Instructor: James S. Nowick, Ph.D. This is the third quarter course in the organic chemistry series. Topics covered include: Fundamental concepts relating to carbon compounds with emphasis on structural theory and the nature of chemical bonding, stereochemistry, reaction mechanisms, and spectroscopic, physical, and chemical properties of the principal classes of carbon compounds. Organic Chemistry 51C is part of OpenChem. Index of Topics: -1:36 Ketone/Aldehyde Reduction -5:56 Grignard Reagents -12:31 Polarity of Grignard Reagent -16:01 Basicity of Grignard Reagent -19:22 Grignard Reagents and Water/Alcohol -21:32 Organolithium Reagent -25:50 Acetylide Anions -34:07 Making Acetylide Anion -38:29 Reactivity of the Carboxylic Acid Family -44:56 Addition-Elimination Reaction -48:12 Examples of Carboxylic Acid Reduction -53:29 Multiple Additions onto Carboxylic Acids -59:50 Leaving Groups -1:08:27 Synthesizing Example -1:16:54 More Examples of Synthesizing