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Lecture 16. Glycobiology & Polyketides, Part 2.

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Logo of University of California Irvine (UCI)University of California Irvine (UCI)
 Weiss, Gregory Alan

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Lecture 16. Glycobiology & Polyketides, Part 2.
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Lec 16. Introduction to Chemical Biology -- Glycobiology & Polyketides -- Part 2
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16
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18
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UCI Chem 128 Introduction to Chemical Biology (Winter 2013) Instructor: Gregory Weiss, Ph.D. Description: Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways. Index of Topics: 0:00:33 Polysaccharides 0:08:45 Fatty Acid Synthase: Paradigm for a Polyketide Synthesis Machine 0:10:58 Plasma Membrane = Lipid Barrier 0:13:44 Hydrolysis of LIpids in Cell Signaling 0:15:26 Prostaglandin Signaling to Coordinate Cell Response 0:16:15 Leukotrienes Mediate Inflammatory Response 0:19:09 Shutting Down the Prostaglandin Pathway at its Start 0:23:39 Converting Fats into Soaps 0:25:54 Diversifying Products from Polyketide Synthases 0:39:54 Fatty Acid Synthase (FAS) Has a Circular Assembly Line 0:44:18 Terpenes: Built from Isoprene (5C) Units 0:56:18 Inhibition of Cholesterol Synthesis 0:57:48 Cyclization of Straight-Chain Precursors by Enzymes