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Lecture 15. Glycobiology & Polyketides.

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Logo of University of California Irvine (UCI)University of California Irvine (UCI)
 Weiss, Gregory Alan

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Lecture 15. Glycobiology & Polyketides.
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Lec 15. Introduction to Chemical Biology -- Glycobiology & Polyketides -- Part 1
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15
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18
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UCI Chem 128 Introduction to Chemical Biology (Winter 2013) Instructor: Gregory Weiss, Ph.D. Description: Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways. Index of Topics: 0:00:19 Carbohydrates 0:03:15 Glycosylated Proteins 0:07:25 Extending Oligosaccharides one Monomer at a Time 0:08:26 More Knee Join Oligosacchardies 0:10:25 Snot and Mucus: Anionic Polysaccharides 0:13:21 N-Linked Glycosides: Added as Complex Oligosaccharides 0:22:56 What is the Function of Glycosylation? 0:25:37 Cell Culture Production of Proteins 0:27:54 Glucoronidation Used to Designate Small Molecules for Excretion 0:29:49 Glucose Homeostasis 0:31:39 Non-Enzymatic Glycosylation 0:35:29 Sweetners: Tase Good for the Calories 0:41:00 Terpenes and Polyketides 0:45:09 Nature Prefers Thioesters for the Claisen 0:48:06 Rapid Exchange of Thioesters 0:49:28 Fatty Acid Synthesis by Polyketide