Lecture 13. Protein Function and Enzymes.
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| Title | Lecture 13. Protein Function and Enzymes. |
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| Alternative Title | Lec 13. Introduction to Chemical Biology -- Protein Function and Enzymes |
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| Part Number | 13 |
| Number of Parts | 18 |
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| License | CC Attribution - ShareAlike 3.0 Unported: You are free to use, adapt and copy, distribute and transmit the work or content in adapted or unchanged form for any legal purpose as long as the work is attributed to the author in the manner specified by the author or licensor and the work or content is shared also in adapted form only under the conditions of this license. |
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| Abstract | UCI Chem 128 Introduction to Chemical Biology (Winter 2013)
Instructor: Gregory Weiss, Ph.D.
Description: Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.
Index of Topics:
0:00:41 Enzymes
0:03:20 Repeat Proteins
0:05:16 Equilibrium Constants
0:06:25 Enzymatic Catalysts = Catalytic Receptors
0:07:03 Michaelis Constant for Measuring Catalysis
0:15:30 The Perfect Enzyme
0:21:29 Kinases: Phosphorylation of Ser/Thr or Tyr
0:34:19 Why Study Single Molecules?
0:37:44 How to Follow Enzymatic Catalysis with Single Walled Carbon Nanotubes
0:41:34 Single Biomolecule Bioelectronics
0:44:24 Before and After Enzyme Attachment
0:46:29 Watching cAMP - Dependent Protein Kinase A
0:49:18 Further Generalization: Protein A Kinase
0:55:55 Lysozyme as a Model Enzyme for Glycosdie Hydrolysis
1:08:22 Proteases Cleave Amide Bonds
1:12:37 Regulation of Proteases Through Pro-Enzymes |
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