Lecture 12. Protein Functions.
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| Title | Lecture 12. Protein Functions. |
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| Alternative Title | Lec 12. Introduction to Chemical Biology -- Protein Functions |
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| Part Number | 12 |
| Number of Parts | 18 |
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| License | You are free to use, adapt and copy, distribute and transmit the work or content in adapted or unchanged form for any legal purpose as long as the work is attributed to the author in the manner specified by the author or licensor and the work or content is shared also in adapted form only under the conditions of this license. |
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| Abstract | UCI Chem 128 Introduction to Chemical Biology (Winter 2013)
Instructor: Gregory Weiss, Ph.D.
Description: Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways.
Index of Topics:
0:15:32 Protein Conformation
0:18:28 All B-Sheet Proteins
0:27:13 WD Proteins Scaffold Together Large Assemblies
0:28:12 Collagen is Formed from a 3-Stranded Coil
0:29:21 All a-Helical Proteins
0:31:40 a/B Proteins
0:33:21 Peptide Binding Domains
0:39:05 Higher Order Assemblies of Proteins
0:41:23 Equilibrium Constants to Describe the Strengths of Non-Covalent Interactions
0:46:54 Following the SPeeds of Reactions
0:49:25 Rates of Non-Covalent Interactions
0:50:16 Typical Rates of Binding
0:53:09 Measuring Biological Potency Through Dose Responsive Curve
0:56:26 Measuring Biological Reponse by ELISA
0:59:36 Steptavidin-Biotin Offers Near Covalent Binding Affinity
1:00:39 Biotinylated Reagents Used Extensively in Chemical Biology
1:03:47 Enxymatic Catalysts = Catalytic Receptors |
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