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Lecture 05. Non-Covalent Interactions, DNA.

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Lecture 05. Non-Covalent Interactions, DNA.
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Lec 05. Introduction to Chemical Biology -- Non-Covalent Interactions, DNA.
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5
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18
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UCI Chem 128 Introduction to Chemical Biology (Winter 2013) Instructor: Gregory Weiss, Ph.D. Description: Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways. Index of Topics: 0:10:56 DNA 0:11:11 The Lennard-Jones Potential 0:14:28 Rouges Gallery of Non-Covalent Interactions 0:21:44 Comparing Energetics 0:25:06 All Biology Involves Water 0:28:36 Receptor-Ligand Interactions 0:33:01 Biooligomers on Earth: Modularity 0:34:35 Form Follows Function to Biology 0:39:51 Non-Covalent Bonding Summary 0:43:31 Structure of DNA: Double Helix 0:49:02 The DNA Bases 0:52:40 The Missing 2-OH of DNA Confers Stability 0:59:25 The DNA Bases are Subject to Modification 1:01:39 Watson-Crick Base Pairs form U-Shape 1:02:35 Molecular Recognition 1:14:13 DNA Intercalation: Untwisting of DNA