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Lecture 03. Reactivity and Arrow Pushing.

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Lecture 03. Reactivity and Arrow Pushing.
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Lec 03. Introduction to Chemical Biology -- Reactivity and Arrow Pushing
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3
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18
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UCI Chem 128 Introduction to Chemical Biology (Winter 2013) Instructor: Gregory Weiss, Ph.D. Description: Introduction to the basic principles of chemical biology: structures and reactivity; chemical mechanisms of enzyme catalysis; chemistry of signaling, biosynthesis, and metabolic pathways. Index of Topics: 0:07:01 What is Life? 0:09:07 Arrows Depict the Overlap of Molecular Orbitals 0:19:57 The Three Components of Orbital Overlap 0:24:27 Charge-Charge or Coulombic Effects 0:26:31 Molecular Orbital Theory Explains the Otherwise Unexplained 0:28:05 Combining Atomic Orbitals 0:39:56 Highest Occupied Molecular Orbital 0:41:57 Lowest Unoccupied Molecular Orbitals (LUMOs) 0:44:08 Anatomy of an Arrow 0:46:38 3 Rules for Mechanistic Arrow-Pushing 1:01:27 H is Always Attached to Something 1:04:48 Hydrogen Bonds 1:08:58 Proton Transfers