Future methods of tissue engineering at Hannover Laser Centre


Formal Metadata

Future methods of tissue engineering at Hannover Laser Centre
Title of Series
Medizinische Hochschule Hannover (MHH)
Exzellenzcluster REBIRTH
Chichkov, Boris N.
Koch, Lothar
Sajti, Laszlo
Gaidukeviciute, Arune
Gittard, Shaun
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Medizinische Hochschule Hannover (MHH), Exzellenzcluster REBIRTH
Release Date
Exzellenzcluster REBIRTH/Medizinische Hochschule Hannover
Production Place

Content Metadata

Subject Area
Leibniz Universität Hannover
Medizinische Hochschule Hannover
Tissue Engineering
Hannover Laser Centre
Cluster of Excellence REBIRTH
Biological Laser Printing
Separation process
Laser Meeting/Interview Textile Scaffolding Printing
Tissue paper
Glass Laser Material
Glass Computer animation Material Gas compressor
Tissue paper Meeting/Interview Experiment indoor Speise <Technik>
Meeting/Interview Cartridge (firearms) Kette <Zugmittel>
Meeting/Interview Experiment indoor Corporal (liturgy)
Meeting/Interview Material
Computer animation Scaffolding
Meeting/Interview Photographic processing Material Kopfstütze
Computer animation
Tissue paper Meeting/Interview Spare part Engine Material
Tissue paper Meeting/Interview
Computer animation
mn all Hanover laser center this is home to several workgroups research in the field of laser-based nanotechnology nanoparticles aggregates
of several to several thousand atoms or molecules there that's extremely small particles a thousand times smaller than the diameter of a hat but what the nanoparticles and laser beams have to do with biomedicine you a great deal of it turns out that the revision using goes within rebirth site interested in developing bio fabrication technologies but these technologies are based on laser techniques 1 of which is two-photon polymerization the we use to photon polymerization to create three-dimensional scaffolds than the ones that have the other technique involves using lasers to produce nanoparticles that's the world and of the final group you visiting here is concerned with studying and developing biological laser-printing about creating to by
laser printing it sounds highly implausible
and yet that's exactly what workgroup 29 is involved in the researchers are aiming to be produced biological tissue the technique
they're using here is called lift pro-poor laser-induced forward transfer a piece of
glass is coated with an absorption layer onto which the biological material i.e. cells is
placed the laser radiation is focused
through the glass on the absorption by here which make promises the pressure of the cost of ontological
material to accelerate in the direction of the names of the restaurants second-class place depending on the last thing to move towards the laser and the design of 3 dimensional structures can be created suffice it to but what
purpose does this serve the following day being or grasping we want to get round the problems of the shortage of donor organs and rejection responses following transplantation and so new organs or tissues are engineered from the patient's cells by way of replacement that this has not been possible so far because only a 2 dimensional array of cells can be engineered in a petri dish here we provide a technique for arranging cells in 3 dimensions enabling them to form real tissue is available in many fields of technology the future
really does belong to nanoparticles and
biomedicine is among them the researchers in what group 30 nanoparticles are producing 0
materials using the laser-based system what's covering the liquid right here on on
gold particles the laser is extracted from a gold chain a 1st step towards the opening up
exciting potential in biomedicine the the only thing that we synthesize laser-generated nanoparticles which has highly pure properties that and we do this in the direction of the drug delivery or especially by economies for different and the medical applications we can also antibacterial nanoparticles and embedding them and who uh and polymeric nanocomposites for example in case the here have hand just a regular I think that when we met silver nanoparticles
which brings antibacterial properties to
this uh the thing that we also work in the direction of the improving the the cellular properties of the biological properties of the medical implants uh to have some similar Corporation and we work in collaboration with at the Hannover Medical and the that in school and also in the that the
research is in workgroup 21 non-native
services on builders in the broadest sense of the word
but they're working on creating time surfaces from polymers appointees synthetic materials
which reproduce the natural environment of the cells
these could in fact a scaffold for the cells and
he began to grow three-dimensionally and thus
develop into something closer to natural to see to see just how powerful that means is being used up
half look at this time the statue of venus and a few micrometres in height and this system is used think suppose for the sensitive laissez faire and and at the beginning of this request and during the exposure process if isn't a solid afterwards during the development process factor there is and I think that the developer and all the rest of the material is washed out so we're in this for the and structural center which has a micrometre scale the but the
research is going to take this even further and that could
mean what you see here on the left is a
CAD template and on the right is a scanning electron microscopy image of 1 of the created structures it resembles fragments
of view the which are responsible for gas exchange in the mammalian now the the
goal of our research is to develop new materials to be used with two-photon polarization to make tissue engineering scaffolds so for example we can use a novel materials that are based on materials in the body to make the artificial and replacement tissues if you have damaged part for example or damaged or by so we can produce capillary systems to replace the wonderful thing about so perhaps a little
too distant future could indeed be possible to
introduce you to see into the place diseased
tissue in the human body and this may be a dream but people working hard
to make a community in the


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