Public health entities around the world do not have the Information Technology (IT) resources and infrastructure necessary for building robust applications for disease surveillance. Using the open-source model and cloud computing infrastructure, an attempt has been made to enable global reporting of some of the parameters around birth defects and potential "causative" environmental factors on a spatial basis. The application includes elements of peer review of reports and preservation of confidentiality of the patients and reporters in novel ways. Spatial aggregation of patient location data provides a summary of occurrence of birth defects worldwide or limited to a region depending on the requirements of the end-user(s)Spatial navigational tools enable the user to drill down to an aggregation level of 1 x 1 degrees square. Peer review and requests for detailed data from data owners occur through search tools and an email interface.