Synthesis of RG-I oligosaccharides
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| Number of Parts | 22 | |
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| License | CC Attribution 3.0 Unported: You are free to use, adapt and copy, distribute and transmit the work or content in adapted or unchanged form for any legal purpose as long as the work is attributed to the author in the manner specified by the author or licensor. | |
| Identifiers | 10.5446/14089 (DOI) | |
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BiosynthesisOligosaccharideChemistryDarmstadtiumOceanBackhoeInclusion (mineral)Mill (grinding)Screening (medicine)MoleculeChemische SynthesePolysaccharideOligosaccharideMonosaccharideEnzymeElectronChemical structureCell wallSubstrat <Chemie>BiosynthesisStereoselectivityLecture/Conference
Transcript: English(auto-generated)
00:03
Hi, let me introduce my PhD project. It is entitled Synthesis of ERG1 oligosaccharides. ERG1 stands for Remnig Electronin-1, and it is a planned polysaccharide. Here on this screen, you can see the structure.
00:22
This structure represents a fragment of ERG1 polysaccharide. And this fragment is the molecule that we are aiming at in our PhD project. But what is special about ERG1? Why would we like to make that? That's because we would like to use this molecule
00:41
as a substrate for enzyme status. We would like to research enzymes which are capable for degrading plant cell wall. But why such a synthesis can be a challenge? As you can see on the screen, the monosaccharide units are connected one to another with this glycosidic linkage.
01:02
And the glycosidic linkage has to be constructed in a certain stereo and rigid selective way. So in our project, we have developed a route which allows this tricky synthesis.