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Why do we get Alzheimer's disease?

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Formale Metadaten

Titel Why do we get Alzheimer's disease?
Autor Tony Wyss-Coray
Herausgeber SLAC National Accelerator Laboratory (SLAC)
Erscheinungsjahr 2006
Sprache Englisch

Inhaltliche Metadaten

Fachgebiet Physik
Abstract Neurodegenerative diseases and Alzheimer's disease (AD) in particular, are among the major health concerns of the elderly in industrialized societies. The cause of AD is unknown and no disease-modifying treatments are available. The disease is characterized clinically by a progressive dementia and pathologically by the accumulation of protein aggregates in the brain and a profound loss of nerve cells. It has also become clear recently that local immune responses are activated in the AD brain and may have a role in the disease. Our laboratory uses genetic mouse models to understand the disease process and to identify potential therapeutic targets.

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