The European Commission and many governments are pushing for Open Science as a paradigm for doing research and publishing results. This talk looks at the interface between Open Science and Open Source software, including topics on not just licensing (the obvious topic) but also about open research project management and its simularities and differences with open source projects and communities. Ending with some recommendations for transferring and leveraging the knowledge and experience of open source for open science projects and maximising open source in the recent huge research programmes.