In this talk I will present the highlights of a new project that was recently launched at New Mexico State University. The project is aimed at developing a new generation of tools and solutions to enhance accessibility of mathematics for students with different degrees of visual acuity. The backbone of the project is the use of techniques drawn from knowledge-based systems, and integrate them to create novel, and hopefully more effective solutions. The project has just received funding from the National Science Foundation and it is in collaboration with researchers from Computer Science, Psychology and Mechanical Engineering.