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Laser rapid prototyping of bioactive materials for medical treatment

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Laser rapid prototyping of bioactive materials for medical treatment
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CC Attribution - NoDerivatives 4.0 International:
You are free to use, copy, distribute and transmit the work or content in unchanged form for any legal purpose as long as the work is attributed to the author in the manner specified by the author or licensor.
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This video demonstrates an easy and fast method for rapid prototyping of medical treatment devices. Burn wounds are very painful and take a very long time to heal. Conventional treatment of burns implies exchange of wound coverages several times per day. By pulsed laser ablation of a metal plate in a water-based monomer solution and simultaneous polymerization, nanoparticles are permanently embedded in a polymer matrix, called microgel. Using electrospinning, these microgels can be easily processed to microfibers for the application as ion-release systems. The release of different bioactive metal ions initiated by the nanoparticles, supports all healing stages and therefore improving the healing process. The presented project is interdisciplinary lead by Prof. Stephan Barcikowski (Chair of Technical Chemistry I at the University of Duisburg-Essen, Vice-Director of the Center for Nanointegration Duisburg-Essen (CENIDE) and Co-founder of the Particular GmbH), Prof. Andrij Pich (Chair of Functional and Interactive Polymers in the DWI-Leibnitz-Institute for Interactive Materials at the RWTH Aachen), Prof. Peter M. Vogt and Prof. Kerstin Reimers (Chair of Plastic, Hand and Reconstructive Surgery at the Hannover Medical School). The principal investigators acknowledge the Deutsche Forschungsgemeinschaft (DFG) for generous founding of the Schwerpunktprogramm 1327.
Keywords
Chemical experiment
Chemical experiment
BurnWoundChemical experiment
Meeting/Interview
Activation energyNanoparticleMeeting/Interview
NanoparticleWoundMeeting/Interview
SolutionCombustion chamberOligomereChemical experiment
Ice frontProcess (computing)Chemical experiment
Ocean currentIce frontProcess (computing)Chemical experiment
NanoparticleGrowth mediumChemical experiment
MoleculeChain (unit)NanoparticleSurface scienceGolgi apparatusMoleculeOligomereCapsule (pharmacy)PolymerProcess (computing)Wave propagationMikrokapselHyperpolarisierung
WalkingProcess (computing)PolymerdispersionChemical experiment
NanoparticleMetalGemstoneChemical experiment
Chemical compoundChemical experiment
Ice frontComposite materialSurface scienceFaserverbundwerkstoffZunderbeständigkeitWoundProcess (computing)Active siteSpinning (polymers)Chemical experiment
ZunderbeständigkeitFunctional groupFaserverbundwerkstoffNanoparticleCapsule (botany)Chemical experiment
Capsule (pharmacy)NanoparticleCell biologyWoundCapsule (botany)FaserverbundwerkstoffFunctional groupEngineering drawing
Process (computing)EnzymeChemical reactionIronMetalCopperSense DistrictCope rearrangementThermoformingChemical experimentMeeting/Interview
Systemic therapyCell (biology)MetalActivity (UML)Meeting/Interview
Trauma (medicine)MedicalizationKorkenNanoparticle
MedicalizationTrauma (medicine)Composite materialNanoparticleLaser ablationChemical experiment
Hydroxybuttersäure <gamma->Tin foilActivation energyWoundProgram flowchart
Transcript: Englisch(auto-generated)