The cytoskeleton drives many essential processes in the cell, such as division, the specification of the division axis, movements, polarization and changes in cell shape. These fundamental processes are naturally essential in the development of any organism, and are on their own already complicated to model or understand. What is the correct level of description of intracellular state if one wants to model the development of multiple cells It is possible to capture the dynamics of the cytoskeleton in some simplified way Alternatively, should we carry the full complexity of these cellular processes in a multicellular model Is this desirable