Plone has a great track record for security but keeping your data, infrastructure and business processes secure is a minefield of best practices and technical considerations. In this talk I will give some practical instructions and resources for implementing security best practices across the organisation and discuss some of the major threats that good security can mitigate. This talk covers security broadly at an organisational level as well as some more specific Web, Plone and Volto considerations. It is intended for a wide audience, not just developers and system administrators.