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The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors

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Logo of Beilstein-Institut zur Förderung der Chemischen WissenschaftenBeilstein-Institut zur Förderung der Chemischen Wissenschaften
 Roper, Kimberley A. Ley, Steven V.

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The application of a monolithic triphenylphosphine reagent for conducting Appel reactions in flow microreactors
Alternative Title
Conducting Appel reactions in flow using a triphenylphosphine monolith
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163
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CC Attribution - NoDerivatives 4.0 International:
You are free to use, copy, distribute and transmit the work or content in unchanged form for any legal purpose as long as the work is attributed to the author in the manner specified by the author or licensor.
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Abstract
Herein we describe the application of a monolithic triphenylphosphine reagent to the Appel reaction in flow-chemistry processing, to generate various brominated products with high purity and in excellent yields, and with no requirement for further off-line purification.
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