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417th Brookhaven Lecture


Formale Metadaten

Titel 417th Brookhaven Lecture
Autor Huilin Li
Herausgeber Brookhaven National Laboratory (BNL)
Erscheinungsjahr 2006
Sprache Englisch

Inhaltliche Metadaten

Fachgebiet Physik
Abstract Proteins that cleave other proteins using a molecule of water, protease complexes are exquisite macromolecular machines involved in a multitude of physiological and cellular reactions. Our structural studies shed light into the inner workings of multi-protein assemblies, and they reveal a surprisingly common strategy for controlled proteolysis employed by the two drastically different machines. Further research will facilitate rational design of drugs for treating Tb infection and Alzheimer's disease.

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