Lymphozyten (Rattus norvegicus) - Cytotoxische Wirkung auf allogenetische Fibroblasten
Formal Metadata
| Title | Lymphozyten (Rattus norvegicus) - Cytotoxische Wirkung auf allogenetische Fibroblasten |
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| Alternative Title | Lymphocytes (Rattus norvegicus) - Cytotoxic Effect on Allogenetic Fibroplasts |
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| License | You are free to use, copy, distribute and transmit the work or content in unchanged form for any legal and non-commercial purpose as long as the work is attributed to the author in the manner specified by the author or licensor. |
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| IWF Signature | E 1462 |
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| Production Year | 1968 |
Technical Metadata
| IWF Technical Data | Film, 16 mm, 78 m ; SW, 7 min |
Content Metadata
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| Abstract | | German | German Einschichtiger Zellrasen von Lewin-Fibroblasten. Bewegung von Lymphozyten (Rattenstamm DA) auf den Fibroblasten am 1. und 2. Tag. Zerstörung der Lewis-Fibroblasten durch DA-Lymphozyten am 3. Tag: Einziehen der Fortsätze, Abheben vom Boden, Zell-Lyse der Fibroblasten. Kontrollversuch mit Fibroblasten vom Rattenstamm DA: keine zytotoxischen Reaktionen der DA-Lymphozyten (Original). | | English | English Lymphocytes from DA rats are cultivated on LEWIS fibroblasts. On days 1 and 2 the DA lymphocytes recognize the foreign histocompatibility antigens on the LEWIS fibroblasts. They begin to proliferate and to differentiate. On day 3 destruction of LEWIS fibroblasts by sensitized DA lymphocytes is beginning. The exat mechanism of this target-cell-destruction is still unknown. As shown in the film, direct contact between aggressor and target cell is necessary for destruction to occur. |
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| Keywords | | German | German | | English | English |
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| IWF Classification | | German | German | | English | English |
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