Lymphozyten (Rattus norvegicus) - Cytotoxische Wirkung auf allogenetische Fibroblasten

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Formal Metadata

Title
Lymphozyten (Rattus norvegicus) - Cytotoxische Wirkung auf allogenetische Fibroblasten
Alternative Title
Lymphocytes (Rattus norvegicus) - Cytotoxic Effect on Allogenetic Fibroplasts
Author
Ax, Wolfgang
Fischer, Hans
Malchow, H.
License
CC Attribution - NonCommercial - NoDerivatives 3.0 Germany:
You are free to use, copy, distribute and transmit the work or content in unchanged form for any legal and non-commercial purpose as long as the work is attributed to the author in the manner specified by the author or licensor.
DOI
IWF Signature
E 1462
Publisher
IWF (Göttingen)
Release Date
1974
Language
Silent film
Producer
IWF
Production Year
1968

Technical Metadata

IWF Technical Data
Film, 16 mm, 78 m ; SW, 7 min

Content Metadata

Subject Area
Abstract
Einschichtiger Zellrasen von Lewin-Fibroblasten. Bewegung von Lymphozyten (Rattenstamm DA) auf den Fibroblasten am 1. und 2. Tag. Zerstörung der Lewis-Fibroblasten durch DA-Lymphozyten am 3. Tag: Einziehen der Fortsätze, Abheben vom Boden, Zell-Lyse der Fibroblasten. Kontrollversuch mit Fibroblasten vom Rattenstamm DA: keine zytotoxischen Reaktionen der DA-Lymphozyten (Original).
Lymphocytes from DA rats are cultivated on LEWIS fibroblasts. On days 1 and 2 the DA lymphocytes recognize the foreign histocompatibility antigens on the LEWIS fibroblasts. They begin to proliferate and to differentiate. On day 3 destruction of LEWIS fibroblasts by sensitized DA lymphocytes is beginning. The exat mechanism of this target-cell-destruction is still unknown. As shown in the film, direct contact between aggressor and target cell is necessary for destruction to occur.
Keywords
Lymphozyten
Leukozytenkultur-Test, gemischter / Methoden
Fibroblasten / Immunologie
Zellbewegung
Zellstruktur
cell structure
cell movement
fibroblasts / Immunology
leucocytes culture-test, mixed / methods
lymphocytes
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AV-Portal 3.9.1 (0da88e96ae8dbbf323d1005dc12c7aa41dfc5a31)